Jan-Hendrik Spille

Work

University of Illinois Chicago

US

University of Illinois at Chicago

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Assistant Professor

US

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University of Illinois at Chicago

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Visiting Research Assistant Professor

US

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Massachusetts Institute of Technology

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Postdoctoral Associate

US

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Rheinische Friedrich Wilhelms Universität Bonn

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Postdoctoral Associate

Germany

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Education

Rheinische Friedrich Wilhelms Universität Bonn

Germany
→
Dr. rer. nat.

Julius-Maximilians-Universitat Würzburg

Germany
→
M. sc. Physics

Julius-Maximilians-Universität Würzburg

Germany
→
B. sc. Physics

Publications

Pol II CTD tracking data

data-set

Pol II tracking data for the TPL-treated case.

data-set

Pol II tracking data for the untreated case.

data-set

Chromatin Binding Enriches RNA Polymerase II in Transcription Condensates

preprint

Characterizing Properties of Biomolecular Condensates Below the Diffraction Limit In Vivo.

Methods in molecular biology (Clifton, N.J.)

journal-article

Igh Locus Polymorphism May Dictate Topological Chromatin Conformation and V Gene Usage in the Ig Repertoire.

Frontiers in immunology

journal-article

Advances in Chromatin and Chromosome Research: Perspectives from Multiple Fields.

Molecular cell

journal-article

Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes.

Molecular cell

journal-article

Pol II phosphorylation regulates a switch between transcriptional and splicing condensates.

Nature

journal-article

A first order phase transition mechanism underlies protein aggregation in mammalian cells.

eLife

journal-article

A CRISPR/Cas9 platform for MS2-labelling of single mRNA in live stem cells.

Methods (San Diego, Calif.)

journal-article

Mediator and RNA polymerase II clusters associate in transcription-dependent condensates

Science

journal-article

qSR: a quantitative super-resolution analysis tool reveals the cell-cycle dependent organization of RNA Polymerase I in live human cells

Scientific Reports

journal-article

Global analysis of double-strand break processing reveals in vivo properties of the helicase-nuclease complex AddAB

PLOS Genetics

journal-article

qSR: A software for quantitative analysis of single molecule and super-resolution data

bioRxiv

journal-article

RNA Polymerase II cluster dynamics predict mRNA output in living cells.

journal-article

Labelling and imaging of single endogenous messenger RNA particles in vivo.

journal-article

The lantibiotic nisin induces lipid II aggregation, causing membrane instability and vesicle budding.

Biophysical Journal

journal-article

The lantibiotic nisin induces lipid II aggregation, causing membrane instability and vesicle budding.

journal-article

Direct observation of mobility state transitions in RNA trajectories by sensitive single molecule feedback tracking.

Nucleic Acids Research

journal-article

Direct observation of mobility state transitions in RNA trajectories by sensitive single molecule feedback tracking.

journal-article

Direct observation of mobility state transitions in RNA trajectories by sensitive single molecule feedback tracking

Nucleic Acids Research

journal-article

Cutting edge: the UNC93B1 tyrosine-based motif regulates trafficking and TLR responses via separate mechanisms.

The Journal of Immunology

journal-article

Cutting edge: the UNC93B1 tyrosine-based motif regulates trafficking and TLR responses via separate mechanisms.

journal-article

Reelin and CXCL12 regulate distinct migratory behaviors during the development of the dopaminergic system.

Development

journal-article

Reelin and CXCL12 regulate distinct migratory behaviors during the development of the dopaminergic system.

journal-article

Nuclear trafficking and export of single, native mRNPs in Chironomus tentans salivary gland cells.

Methods in molecular biology (Clifton, N.J.)

journal-article

Dynamic three-dimensional tracking of single fluorescent nanoparticles deep inside living tissue.

Optics Express

journal-article

Dynamic three-dimensional tracking of single fluorescent nanoparticles deep inside living tissue.

journal-article

A cylindrical zoom lens unit for adjustable optical sectioning in light sheet microscopy

Biomedical Optics Express

journal-article

Rotational Diffusion of the alpha(2a) Adrenergic Receptor Revealed by FlAsH Labeling in Living Cells

Biophysical Journal

journal-article